Fully automated whole-exome sequencing (WES) 
on the AVENIO Edge Liquid Handling System

• No prior NGS and/or automation experience required
• As little as 20 minutes of deck setup time for the entire WES workflow
• Automated quantification, normalization and pooling
• Complementary support team to help you along the way

From sample to sequencing, with automation and support at every step

KAPA HyperExome V2 Probes deliver superior whole-exome sequencing (WES) coverage of recent versions of ACMGv3.1, RefSeq, CCDS, ClinVar, Ensembl, and COSMIC genomic databases. This design reduces sequencing requirements, with a compact capture target of 43.2 Mb covering 37.5 Mb of key content.  

KAPA HyperExome V2 Probes on the AVENIO Edge Liquid Handling System

Sequencing metrics for 8-plex libraries (pre-capture pooling) created with the AVENIO Edge HyperPrep Kit. Input = 100 ng NA12878 DNA; n=24. 60 M high-quality reads 2x150bp were analyzed following sequencing on an Illumina® NovaSeq™ 6000 System.

Review the resources below to learn how the combination of the AVENIO Edge Liquid Handling System and the KAPA Hyper Exome V2 Workflow enables you to bring your WES in house.

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