PCR-based (qPCR or dPCR) or the recently-adopted NGS-based methods, including comprehensive genomic profiling of solid tumors from FFPE tissue or liquid biopsy samples, are commonly used in molecular diagnostics labs.
However, for such undertakings, significant challenges need to be overcome—especially with respect to the requirement for simpler assays, more flexible throughput, shorter turnaround time, and, most importantly, easier data analysis and interpretation. These breakthroughs will translate NGS to a more accessible companion diagnostics tool, similar to how PCR-based assays are used today.
To learn more about overcoming barriers to adoption of NGS in clinical labs read this article:
Accelerating clinical adoption of next-generation sequencing
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